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Nov 1 , 2024
Antimicrobial resistance, the process of microorganisms developing defences against treatment, poses a huge challenge to healthcare around the world. It is estimated to cause 1.2 million deaths globally and cost the NHS at least 180 million per year.
Infections in the bloodstream can become resistant to antibiotics and lead to the life-threatening condition, sepsis. Once the infection has reached a stage of sepsis there is a high probability that patients will rapidly develop organ failure, shock, and even death.
Some patients have more antimicrobial resistance than others, due to previous exposure to antibiotics, their genetics and even diet, which can alter their microbiome.
Now, scientists are harnessing the power of AI to assess the antimicrobial resistance of patients in intensive care units ICUs and identify sepsis-causing bloodstream infections.
Researchers from across King's College London and clinicians at Guy's and St Thomas' NHS Foundation Trust have collaborated in this interdisciplinary study – which they hope will help to improve outcomes of critically ill patients.